Cardiology research, memory and fancy

At February 12, 2010
By Yori Yuliandra
In Story of Mine, Think English, Think Pharmacy, Think Student
5

I suddenly got a deep feeling to memorize and write down one of my researches (sorry guys, I am pretending like I am a great researcher who used to conduct many researches and studies from any different fields, haha…). Yeah, honestly it was the one and only research I ever conducted :(. But you get to believe me that I got some other projects and papers in several occasions, I did… Come on, believe it…

By the way, I with my lab partners conducted an experimental research in the lab of pharmacology. Under a pretty assistance of “you know who”, we studied the pharmacological action of a plant named “akar mambu”. This plant had previously been investigated to have a blood pressure-lowering activity upon normotensive animal. We tried to figure out how far it could lower the blood pressure of hypertensive animal.

Performing this research made me know sufficiently about

An anti hypertensive effect of Connarus grandis Jack leaves ethanolic extract has been investigated on anesthetized two kidney one clipt (2K1C) Goldblatt hypertensive rats. Four groups of animals were treated with the extract at doses of 10, 20, 40 and 80 mg/kg BW intra peritoneally. These doses were repeated every half an hour. Blood pressure (systolic, diastolic, mean) and heart rat were measured ten miknutes after each dose. As comparisons, a groups of control animals (treated with saline) and another treated with Captopril (2.5 mg/kg) were used. Results showed that the extract reduced SBP, DBP and MAP especially at dose of 20 mg/kg. The potency of this extract in reducing blood pressure was lower as compared to those given by Captopril.